A Forbidden Love – The Science Behind CBD

A Forbidden Love-The Science Behind CBD

As more research is being processed, a vast majority of clinicians view CBD as a nutrient that our body needs. The comprehensive impact of CBD and other cannabinoids on the human body is still being discovered by scientists. There is one certainty- and that is that CBD oil is a powerful compound which can provide natural healing properties in multiple health conditions.

For the time being, specific studies of CBD and Hemp compounds on the human body are limited. However, with recent legislative changes there is a heavy swing in interest into this untapped market from multiple angles. Theres obviously the monetary perspective, where investors are trying to cash in and make a quick buck. However, with the legislative change it has also opened up the doors for research centers to complete in depth studies to what the positive impacts of CBD Oil and Hemp truly are. Believe it or not, there was actually a time when Hemp was at the forefront of US Government research. The National Institute on Drug Abuse was attempting to prove the negative impacts of hemp to support the war on drugs, which did not play out as expected. 

Amidst this research, scientists discovered the endocannabinoid system (ECS). The System was actually named after the plant that led them to the discovery of the system. ECS is a valuable system as it works similar to a lock and key system; intricately intertwined to systems such as the digestive, immune and nervous system. The ECS adapts to stress by promoting balance and homeostasis.

The ECS consists of cannabinoid receptors, CB1 and CB2.  These receptors work as simple as they sound, picking up biochemical cues which ultimately affect surrounding cells. CB1 receptors are mainly found in the brain and affect brand development, coordination, sleep, learning, appetite, anxiety, pain, addiction, nausea and vomiting. CB2 receptors are mainly found in the peripheral nervous system, immune system,  gastrointestinal tract and various other organs. CB2 activation affects immune responses, such as inflammation and promotes neuroplasticity, which places the brain into a malleable state allowing humans to learn and form neural connections throughout life. 

CBD does not directly bind to the CB1 and CB2 receptors but it does indirectly influence them. That means the presence of CBD can change the binding of other molecules.This in particular is why a small amount of CBD in cannabis can influence the psychoactivity of THC.  Some of the receptor systems that CBD impacts include: 

-Serotonin Receptors- When CBD interacts with this receptor it is known to alleviate anxiety, addiction, appetite loss, insomnia, pain and nausea.

-Vanilloid Receptors- When activated by CBD, they may ease pain and inflammation.

-Orphan Receptors or GPR55 – When overactive, it can trigger high blood pressure, osteoporosis and the spread of cancer cells. CBD may help deactivate the GPR55 receptor.

-Nuclear Receptors- These receptors regulate energy, insulin and metabolism. Also, it may help stop the progression of Alzheimer’s. CBD may help these receptors kick in. 

The history of hemp and CBD is rich and unfortunately has been suppressed for many years due to the US War on drugs. WIth that being said, now that new legislation has legalized hemp and CBD, we are starting to see much more data and research being made available which is helping solidify the use of CBD oil as part of daily regimen may help improve certain conditions.

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